Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection Mac Aogáin, Micheál and Miajlovic, Helen and Moloney, Geraldine and Chotirmall, Sanjay H. and Rogers, Thomas R. and Smith, Stephen G. J.,, 3, e005061 (2016), doi = https://doi.org/10.1099/jmmcr.0.005061, publicationName = Microbiology Society, issn = , abstract= Introduction: Globally, extra-intestinal pathogenic Escherichia coli are one of the predominant causative agents of bacteraemia. Case presentation: This case report outlines a presentation of community-acquired pyelonephritis and secondary bloodstream infection in an 81-year-old man. Laboratory investigations revealed that the causative isolate was a multi-drug-resistant E. coli of a novel multi-locus sequence type. This sequence type (ST) was designated ST-458 and was most closely related to the globally prevalent ST-131 lineage. Conclusion: This is the first report of a novel E. coli ST, ST-458, which caused pyelonephritis and bacteraemia. , language=, type=