1887

Abstract

Lyme disease is a tick-borne illness caused by the spirochete and is widely reported in the USA, Central Europe, South East Asia and Latin America. Until recently, no scientific report regarding Lyme disease in Nepal had been published.

A 32-year-old, previously healthy female visited the hospital with a history of joint pains, fatigue, neck stiffness, tingling sensation and headache. She was initially treated for typhoid fever, brucellosis and malaria, but did not show significant improvement. Doxycycline was prescribed empirically for 3 weeks for the treatment of suspected tick-borne illness. A two-tiered immunoglobulin laboratory testing confirmed . She developed post-treatment Lyme disease syndrome after completion of antibiotic therapy.

To the best of our knowledge, this is the first report of Lyme disease in Nepal and probably the first documented case of post-treatment Lyme disease syndrome in Asia. Lyme disease might have been overlooked in Nepal and, therefore, patients having clinical signs and symptoms similar to Lyme disease should not be disregarded in differential diagnosis.

Loading

Article metrics loading...

/content/journal/jmmcr/10.1099/jmmcr.0.005128
2018-03-01
2024-04-25
Loading full text...

Full text loading...

/deliver/fulltext/jmmcr/5/3/jmmcr005128.html?itemId=/content/journal/jmmcr/10.1099/jmmcr.0.005128&mimeType=html&fmt=ahah

References

  1. Skar G, Simonsen K. Tick, Disease, Lyme. In StatPearls [Internet] Treasure Island, FL: StatPearls Publishing; 2017 [Updated 2017 Feb 7]
    [Google Scholar]
  2. Steere AC, Malawista SE, Snydman DR, Shope RE, Andiman WA et al. Lyme arthritis: an epidemic of oligoarticular arthritis in children and adults in three Connecticut communities. Arthritis Rheum 1977; 20:7–17 [View Article][PubMed]
    [Google Scholar]
  3. Aucott JN, Rebman AW, Crowder LA, Kortte KB. Post-treatment Lyme disease syndrome symptomatology and the impact on life functioning: is there something here?. Qual Life Res 2013; 22:75–84 [View Article][PubMed]
    [Google Scholar]
  4. Weisshaar E, Schaefer A, Scheidt RR, Bruckner T, Apfelbacher CJ et al. Epidemiology of tick bites and borreliosis in children attending kindergarten or so-called "forest kindergarten" in southwest Germany. J Invest Dermatol 2006; 126:584–590 [View Article][PubMed]
    [Google Scholar]
  5. Centers for Disease Control and Prevention Recommendations for test performance and interpretation from the Second National Conference on Serologic Diagnosis of Lyme Disease. MMWR Morb Mortal Wkly Rep 1995; 11:590–591
    [Google Scholar]
  6. Sharma A, Guleria S, Sharma R, Sharma A. Lyme disease: a case report with typical and atypical lesions. Indian Dermatol Online J 2017; 8:124–127 [View Article][PubMed]
    [Google Scholar]
  7. Hashimoto Y, Kawagishi N, Sakai H, Takahashi H, Matsuo S et al. Lyme disease in japan. analysis of borrelia species using rRNA gene restriction fragment length polymorphism. Dermatology 1995; 191:193–198[PubMed] [Crossref]
    [Google Scholar]
  8. Centers for Disease Control and Prevention Signs and symptoms of untreated lyme disease. www.cdc.gov/lyme/signs_symptoms/index.html
  9. Lantos PM. Chronic Lyme disease. Infect Dis Clin North Am 2015; 29:325–340 [View Article][PubMed]
    [Google Scholar]
  10. Wormser GP, Dattwyler RJ, Shapiro ED, Halperin JJ, Steere AC et al. The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis 2006; 43:1089–1134 [View Article][PubMed]
    [Google Scholar]
  11. Centers for Disease Control and Prevention Statistics. www.cdc.gov/lyme/stats/humancases.html
  12. Rizzoli A, Hauffe H, Carpi G, Vourc HG, Neteler M et al. Lyme borreliosis in Europe. Euro Surveill 2011; 16:19906
    [Google Scholar]
  13. Aucott JN. Posttreatment Lyme disease syndrome. Infect Dis Clin North Am 2015; 29:309–323 [View Article][PubMed]
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/jmmcr/10.1099/jmmcr.0.005128
Loading
/content/journal/jmmcr/10.1099/jmmcr.0.005128
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error