1887

Abstract

is a coagulase-negative staphylococcus that has been reported in several cases as a human pathogen. However, it has rarely been reported as pathogen in native bone. Furthermore, the reported MIC levels noted in the literature for vancomycin were <2 µg ml making vancomycin a first line choice for infected patients.

We report a case of causing osteomyelitis of the lumbar spine and bacteraemia and resulting in sepsis and ultimately the demise of a patient despite appropriate prolonged antibiotic therapy.

has been reported as a human pathogen since 1983 when it was discovered. We report a case involving native bone infection which is rare in the absence of mechanical hardware. Furthermore, this strain had an elevated MIC for vancomycin which has not been reported in the literature.

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2017-09-25
2024-04-24
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References

  1. Allignet J, Aubert S, Dyke KG, El Solh N. Staphylococcus caprae strains carry determinants known to be involved in pathogenicity: a gene encoding an autolysin-binding fibronectin and the ica operon involved in biofilm formation. Infect Immun 2001; 69:712–718 [View Article][PubMed]
    [Google Scholar]
  2. Devriese LA, Poutrel B, Kilpper-Balz R, Schleifer KH et al. Staphylococcus gallinarum and Staphylococcus caprae, two new species from animals. Int J Syst Bacteriol 1983; 33:480–486 [View Article]
    [Google Scholar]
  3. Ross TL, Fuss EP, Harrington SM, Cai M, Perl TM et al. Methicillin-resistant Staphylococcus caprae in a neonatal intensive care unit. J Clin Microbiol 2005; 43:363–367 [View Article][PubMed]
    [Google Scholar]
  4. Seng P, Barbe M, Pinelli PO, Gouriet F, Drancourt M et al. Staphylococcus caprae bone and joint infections: a re-emerging infection?. Clin Microbiol Infect 2014; 20:O1052–O1058 [View Article][PubMed]
    [Google Scholar]
  5. Benedetti P, Pellizzer G, Furlan F, Nicolin R, Rassu M et al. Staphylococcus caprae meningitis following intraspinal device infection. J Med Microbiol 2008; 57:904–906 [View Article][PubMed]
    [Google Scholar]
  6. D'Ersu J, Aubin GG, Mercier P, Nicollet P, Bémer P et al. Characterization of Staphylococcus caprae clinical isolates involved in human bone and joint infections, compared with goat mastitis isolates. J Clin Microbiol 2016; 54:106–113 [View Article][PubMed]
    [Google Scholar]
  7. Henry CR, Schwartz SG, Flynn HW. Endophthalmitis following pars plana vitrectomy for vitreous floaters. Clin Ophthalmol 2014; 8:1649 [View Article][PubMed]
    [Google Scholar]
  8. Kato J, Mori T, Sugita K, Murata M, Ono Y et al. Central line-associated bacteremia caused by drug-resistant Staphylococcus caprae after chemotherapy for acute myelogenous leukemia. Int J Hematol 2010; 91:912–913 [View Article][PubMed]
    [Google Scholar]
  9. Vandenesch F, Eykyn SJ, Bes M, Meugnier H, Fleurette J et al. Identification and ribotypes of Staphylococcus caprae isolates isolated as human pathogens and from goat milk. J Clin Microbiol 1995; 33:888–892[PubMed]
    [Google Scholar]
  10. Shuttleworth R, Behme RJ, Mcnabb A, Colby WD. Human isolates of Staphylococcus caprae: association with bone and joint infections. J Clin Microbiol 1997; 35:2537–2541[PubMed]
    [Google Scholar]
  11. Tande AJ, Osmon DR, Greenwood-Quaintance KE, Mabry TM, Hanssen AD et al. Clinical characteristics and outcomes of prosthetic joint infection caused by small colony variant staphylococci. MBio 2014; 5:e01910-14 [View Article][PubMed]
    [Google Scholar]
  12. Zhu W, Sieradzki K, Albrecht V, Mcallister S, Lin W et al. Evaluation of the biotyper MALDI-TOF MS system for identification of Staphylococcus species. J Microbiol Methods 2015; 117:14–17 [View Article][PubMed]
    [Google Scholar]
  13. Kanda K, Suzuki E, Hiramatsu K, Oguri T, Miura H et al. Identification of a methicillin-resistant strain of Staphylococcus caprae from a human clinical specimen. Antimicrob Agents Chemother 1991; 35:174–176 [View Article][PubMed]
    [Google Scholar]
  14. Barelli C, Minto EC, Martinez R, Darini AL, da Costa Darini A. Evaluation of the antimicrobial susceptibilities of coagulase-negative staphylococci by E-test. Rev Latinoam Microbiol 1999; 41:67–72[PubMed]
    [Google Scholar]
  15. Shin JH, Kim SH, Jeong HS, Oh SH, Kim HR et al. Identification of coagulase-negative staphylococci isolated from continuous ambulatory peritoneal dialysis fluid using 16S ribosomal RNA, tuf, and SodA gene sequencing. Perit Dial Int 2011; 31:340–346 [View Article][PubMed]
    [Google Scholar]
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